With the May update of Windows 10, the error 0x80070643 also came. Most of the time, the problem lies with Windows Defender..
If you are encountering error code 0x80070643 on your computer, you are not alone with it. Because since the last major update in May 2019, many Windows users have been struggling with this error. Usually this error occurs when trying to update your system or a program.
The .NET Framework plays an important role in the installation of system updates. If this file is not available on your computer or is damaged, problems can occur during the update:
The error code is related to Windows Defender. Windows could then usually not update the program correctly. You can try to fix the error by updating the Defender yourself: